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A Probiotic Mixture of <i>Lactobacillus rhamnosus</i> LR 32, <i>Bifidobacterium lactis</i> BL 04, and <i>Bifidobacterium longum</i> BB 536 Counteracts the Increase in Permeability Induced by the Mucosal Mediators of Irritable Bowel Syndrome by Acting on Zonula Occludens 1.

Int J Mol Sci · 2025 · PMC11942538 · PMID 40141298

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The highest dose of Serobioma induced a significant increase in JAM-A expression compared to Caco-2 cells that were incubated with growth medium alone, while when co-incubated with IBS-D and IBS-M supernatants, it induced an increase in JAM-A expression which did not reach statistical significance ( Figure 5 C). 3.

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