Barely Significant
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Harnessing Plasma Biomarkers to Predict Immunotherapy Outcomes in Hepatocellular Carcinoma: The Role of cfDNA, ctDNA, and Cytokines.

Int J Mol Sci · 2025 · PMC11942713 · PMID 40141436

1
hedged sentence
0.0530
closest p · 1.1× alpha
0.0530
boldest claim

The sentences

showed a trendp = 0.053so close (0.05 < p ≤ 0.1)
Although not statistically significant, higher TGF-β levels at three months post-treatment initiation showed a trend toward association with worse outcomes [mean (standard deviation) 43.2 (28.2) pg/mL vs. 29.6 (46.9) pg/mL, p = 0.053] ( Figure 5 ).

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