highly significantp < 0.001
Most notably, the TTH demonstrated a highly significant divergence between groups ( p < 0.001), with the S group demonstrating the shortest median TTH of 94 s (IQR: 86–98) compared to 256 s (IQR: 245–295) in the C group and 120 s (IQR: 78–131) in the T group, as presented in Table 10 and Figure 6 . 4.