The anti-TLR4 used at a high concentration significantly inhibited TNF-α release induced by the invasive NTHi strain 08-252 as compared to the isotype control ( p < 0.05); at low concentration, the inhibitory effect was noted, but it did not reach statistical significance ( p > 0.05) ( Figure 3 A).
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Inflammatory Responses to Non-Typeable <i>Haemophilus influenzae</i> Clinical Isolates from Invasive and Non-Invasive Infections.
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