Notably, their observation of an increasing trend in GBC incidence among specific populations, particularly in males and younger individuals aged < 50 years, provides a temporal perspective that complements our cross-sectional meta-analysis findings.
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Epidemiology of gall bladder cancer and its prevalence worldwide: a meta-analysis.
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Other covariates, such as study design, geographical region, and tumor stage, also exhibit p -values approaching significance as summarized in Table 3 .
Overall, there is a notable trend of varying prevalence across different geographic regions.