Among the CD4 + T cells in the lungs and HLNs, an increased proportion of T central memory (TCM) cells (CCR7 + CD45RA – ) was observed in CLAD, compared with control and IPF; however, this did not reach statistical significance ( Figure 1, H–J ).
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NKG2D blockade impairs tissue-resident memory T cell accumulation and reduces chronic lung allograft dysfunction.
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