The comparison of variant frequencies between Cohort 1 and 2 identified 34 significant hits, involving variants in 20 genes with nominally significant differences in frequencies across the two cohorts; no variant showed a statistically significant difference in prevalence between the two groups after correction for multiple comparisons.
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CYP3A Genotype Is Associated With Variability in the Exposure and Clearance of the Novel Oncogenic Transcription Inhibitor Lurbinectedin.
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