The inverse relationship between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and testosterone in adult males in the United States: a cross-sectional study based on the NHANES database.

Front Endocrinol (Lausanne) · 2025 · PMC11949807 · PMID 40162320

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When NHHR was categorized into quartiles, using the lowest quartile (Q1) as the reference group, Model 3 demonstrated that participants in the highest quartile (Q4) had significantly lower testosterone levels, with β = -54.98 (95% CI: -86.21 to -23.74, P = 0.001), and a significant trend test.

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