Early stage of metabolic dysfunction associated steatotic liver disease disrupts circadian rhythm and induces neuroinflammation in rats.

Sci Rep · 2025 · PMC11950343 · PMID 40148513

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0.0800

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a statistical trendp < 0.08so close (0.05 < p ≤ 0.1)

Furthermore, 5 additional mediators showed a statistical trend ( p < 0.08) towards either over- or under-expression.

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showed a trendp < 0.08so close (0.05 < p ≤ 0.1)

The frontal cortex of the same animals is characterised by the significant overexpression of 10 mediators and 7 more showed a trend towards being overexpressed ( p < 0.08), with a total of 17 altered mediators representing 22% of the proteins detected (Fig. 8 a, b).

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