( 57 ) indicated that male W88C hete mice exhibited significantly increased activity levels in the open-field test, while female W88C hete mice showed a trend toward decreased PPI.
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<i>WWC1</i> mutation drives dopamine dysregulation and synaptic imbalance in Tourette's syndrome.
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Despite the notable impact of TS, research into its underlying mechanisms and targeted treatments has been limited, with an increasing trend in diagnoses ( 7 , 8 ).