Importantly, whole-genome sequencing showed a trend for increased DNA damage in primary DM DNMT3A AML samples, especially when DNMT3A mutations are located at the DNMT3A-TDG interaction interface. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2024 Sep 3; Accepted 2024 Nov 21; Collection date 2025 Mar 25.
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Double mutant DNMT3A AML: a unique subtype experiencing increased DNA damage and poor prognosis.
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