Identification of a neuron-specific ferroptosis in the neurodegenerative mucopolysaccharidosis III model.

Front Mol Biosci · 2025 · PMC11959000 · PMID 40171043

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did not reach statistical significanceno p-value reported

In MPSIIIB model, ACSL4 showed a tendency towards increased expression (although this did not reach statistical significance), while LPCAT3 was significantly upregulated in aging mice.

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almost significantno p-value reported

We observed a significant increase in the abundance of TFR1 mRNA and an almost significant increase of ZIP14 mRNA levels in 2-month-old MPSIIIB mice compared to age-matched WT mice ( Figures 1B, C ).

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