Variations in stiffness and structure of the human aorta along its length.

A GG-corrected RM ANOVA revealed a highly significant effect of location on elastin density ( p < 0.001), with notable differences between TA and IFR ( p < 0.001), TA and dAA ( p < 0.001), SC and IFR ( p < 0.001), and SC and dAA ( p < 0.001).

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For TA, the directional dependency approached significance, with p = 0.116 at 50 kPa and p = 0.067 at 75 kPa.

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An increasing trend in the opening angle was observed from TA to IFR (TA: 157.77°, SC: 183.78°, IFR: 201.93°), followed by a decrease at dAA (151.15°).

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The intimal and adventitial radii of the aorta exhibited a decreasing trend along the length, most notably until the IFR, as shown in Fig. 2 B.

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