Mendelian Randomization and Bayesian Colocalization Analysis Implicate Glycoprotein VI as a Potential Drug Target for Cardioembolic Stroke in South Asian Populations.

MR associations between genetically proxied GP6 and overall stroke risk and ischemic stroke risk showed the same direction as cardioembolic stroke but did not reach statistical significance after multiple testing correction (OR wald ratio , 1.63 [95% CI, 1.25–2.13]; P =3.7×10 −4 ; FDR=0.22; Figure 2 ; Table S3 ).

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