For instance, Aneurinibacillaceae displayed a potential causal relationship not only with endometrial cancer [OR (95% CI) 1.384 (1.005–1.905), P = 0.046].Though this association was marginally significant and did not survive multiple testing correction.
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Gut microbiota, blood metabolites, & pan-cancer: a bidirectional Mendelian randomization & mediation analysis.
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In a reverse MR analysis, we identified a nominally significant bidirectional causal relationship between colorectal cancer and one gut microbiota species, Syntrophorhabdia , at the threshold of P IVW < 0.05 [OR (95% CI) 1.011 (1.000–1.023), P = 0.046], as reported in Table S3 .