Barely Significant
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Causal relationships between serum metabolites and coronary heart disease risk: a mendelian randomization study.

Front Genet · 2025 · PMC11965349 · PMID 40182922

Europe PMCDOI
2
hedged sentences
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closest p · 1.0× alpha
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boldest claim

The sentences

nominally significantp < 0.05actually significant
A total of 26 metabolites comprising 15 known metabolites and 11 unknown metabolites displayed a nominally significant relationship ( p < 0.05, IVW method) with CHD risk ( Table 1 ).

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highly significantno p-value reported
Firstly, the instrumental variables (IVs) must demonstrate a direct and highly significant association with the exposure, which in this case is serum metabolites.

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