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Functional vs Structural Cortical Deficit Pattern Biomarkers for Major Depressive Disorder.

JAMA Psychiatry · 2025 · PMC11966481 · PMID 40172866

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The higher ReHo and CBF-derived RVI not only indexed the MDD diagnosis effects across samples but also captured the depression symptom severity effects, whereas the association between structural RVI and symptom severity did not reach statistical significance.

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