Participants with abnormal glucose tolerance test results had higher glypican-4 level than healthy controls throughout the whole pregnancy; however, the observed difference failed to reach statistical significance, potentially attributable to the smaller postpartum follow-up sample size and the inadequate follow-up time for OGTT assessment of glucose metabolism.
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Glypican-4 trajectory predicts the risk of gestational diabetes mellitus and the requirement for insulin therapy during pregnancy.
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