Administration Strategy-Dependent Mechanisms and Effects of Human Adipose Tissue Stem Cell Extracellular Vesicles in Mouse Allergic Rhinitis Treatment.

The ND group showed a decreasing trend, albeit the difference was not significant.

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Consequently, this variation was designated as “the therapeutic effect of PBS..” The results demonstrated that, irrespective of the specific condition (e.g., scratching the nose, runny nose, or sneezing), the therapeutic effect of PBS exhibited a favorable trend over time ( Fig. 4E ).

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Although only the ND group had a significant reduction in sIgG4 level, the other two groups also showed a strong trend toward reduction when compared with the AR one ( Fig. 2A , B ).

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