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Amelioration of signaling deficits underlying metabolic shortfall in TREM2<sup>R47H</sup> human iPSC-derived microglia.

FEBS J · 2025 · PMC11970715 · PMID 39726135

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TREM2 R47H ‐succinate MCM but not TREM2 R47H ‐citrate MCM, was shown to additionally increase spare respiratory capacity to the levels of untreated neurons, although it did not reach statistical significance (Fig. 6H ).

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