Home blood pressure-lowering effect of esaxerenone vs trichlormethiazide for uncontrolled hypertension: a prespecified subanalysis of the EXCITE-HT randomized controlled study by age subgroup.

Hypertens Res · 2025 · PMC11972961 · PMID 40189653

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showed a trendno p-value reported

This is consistent with a previous phase 3 study of esaxerenone that showed a trend towards a greater BP-lowering effect in older patients and those with lower renin activity [ 27 , 36 ].

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