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DAP12-associated synthetic antigen receptors enable multi-targeting of T cells with independent chimeric receptors in a small genetic payload.

iScience · 2025 · PMC11978328 · PMID 40201126

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The CD133/HER2-dual SAR T cells did appear to have a slight proliferative advantage compared to the respective single-SAR T cells, but the difference did not reach statistical significance ( Figures 5 E and S5 B).

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