Development of bacterial resistance in Germany from 2008 to 2022 - major culprit pathogens, antibacterial drugs, and prescribing practices.

For these pathogens, the balance between rising and declining or stable trends is relatively even, making it difficult to determine a clear trend.

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When examining the development of DDD prescriptions, it is remarkable that the consumption of most of these drugs, except for sulfamethoxazole-trimethoprim, has shown an increasing trend in recent years (Bindel and Seifert 2024a ).

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