Alterations of Fat and Ketone Body Metabolism in ALS and SMA-A Prospective Observational Study.

Eur J Neurol · 2025 · PMC11979353 · PMID 40200760

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amyotrophic lateral sclerosis fatty acids ketone bodies metabolic alterations spinal muscular atrophy Interestingly, the control group showed the opposite phenomenon regarding total ketone body levels in relation to BMI: Subjects with higher BMI showed a trend towards lower ketone body levels (52.80 μmol/L (IQR 40.25–99.60)) compared to those with lower BMI (100.40 μmol (IQR 45.70–245.55); p = 0.10).

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