Epigenetic profiles integrated with transcriptomic reveal the difference between COPD and PRISm in KOCOSS-NIH.

Funct Integr Genomics · 2025 · PMC11982123 · PMID 40205238

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marginal significanceno p-value reported

In particular, the significant CpG site detected in KOCOSS-NIH, considering BMI, smoking status, cell type heterogeneity, and batch effect was only one, cg21259808 of HYDIN, and cg03074225 and cg26186239 of EEF1A2, cg06458358 of ARHGEF10, cg08093537 of FADS2, cg00451635, cg07406359, cg06713374 of EMP2 showed marginal significance (Table 3 ).

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did not reach statistical significanceno p-value reported

While EPCAM displayed differential methylation patterns based on gender, age, and smoking, it did not reach statistical significance in our analysis.

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