The clinical impact of prophylactic concomitant left atrial appendage occlusion during cardiac surgery: A systematic review and meta-analysis.

Am Heart J Plus · 2025 · PMC11987691 · PMID 40224643

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0630

boldest claim

The sentences

failed to reach statistical significancep = 0.051so close (0.05 < p ≤ 0.1)

2 ) failed to reach statistical significance (RR: 1.15; 95 % CI: 1.00 to 1.32; p = 0.051; I 2 = 64 %). 3.7.

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just failed to reach statistical significancep = 0.063so close (0.05 < p ≤ 0.1)

At 6 years after surgery, the estimated freedom from thromboembolic complications was higher in the LAAO group, 96.7 % (95 % CI 95.6–97.9 %) and 95.2 % (95 % CI 93.8–96.6 %) for the LAAO and no LAAO groups, respectively, but the difference just failed to reach statistical significance ( p = 0.063).

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