Sex-Related Analgesic Effects of Opioid-Based Anesthesia and Low-Opioid Anesthesia with Non-Opioid Postoperative Analgesia-A Clinical Observational Study.

J Clin Med · 2025 · PMC11989283 · PMID 40217614

Europe PMC DOI

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closest p · 0.2× alpha

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a negative trendp = 0.01actually significant

The analgesic trajectory in women and men undergoing LOA presented a negative trend, but the pain intensity at 0–2, 2–6, 6–12, and 12–24 h in women was statistically lower than that of the OBA group ( p = 0.01, p = 0.008, p = 0.002, and p = 0.001).

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