Barely Significant
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Clinicopathological Characteristics of Extrapulmonary Neuroendocrine Carcinomas: Treatment Responses and Survival Outcomes: Single-Center Experience.

J Clin Med · 2025 · PMC11989432 · PMID 40217714

3
hedged sentences
0.0650
closest p · 1.3× alpha
0.1820
boldest claim

The sentences

did not reach statistical significancep = 0.065so close (0.05 < p ≤ 0.1)
Among 2 L regimens, irinotecan-based treatments exhibited a slightly better PFS (4.8 months) compared to taxane-based regimens (3.2 months), though this difference did not reach statistical significance ( p = 0.065) ( Figure 5 ).

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a numerical trendp = 0.182not close (p > 0.1)
carboplatin–etoposide) showed a numerical trend favoring cisplatin–etoposide (13.1 vs. 7.1 months, p = 0.182).

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a notable trendno p-value reported
However, a notable trend emerged regarding PFS.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.