Prognostic Value of the C-PLAN Index in Metastatic Renal Cell Carcinoma Treated with Nivolumab.

J Clin Med · 2025 · PMC11989473 · PMID 40217668

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

a trend toward significancep = 0.067so close (0.05 < p ≤ 0.1)

showed a trendp = 0.067so close (0.05 < p ≤ 0.1)

Similarly, IMDC risk classification showed a trend toward significance in univariate analysis (HR = 2.08, 95% CI: 0.86–5.00, p = 0.067) but did not retain independent prognostic value in the multivariate analysis (HR = 1.05, 95% CI: 0.37–2.97, p = 0.994).

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a trend towards significanceno p-value reported

The ORR showed no significant difference between the good and poor C-PLAN index groups ( p = 0.065), although there was a trend towards significance.

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did not reach statistical significanceno p-value reported

While DCR was significantly associated with the C-PLAN index, ORR did not reach statistical significance, though it demonstrated a trend toward significance.

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