Ultra-Low-Dose Inhalation of Melphalan as an Additional Treatment for COVID-19-Associated Pneumonia.

With a significantly more severe initial clinical condition of MG patients at the beginning of MEL therapy, a positive trend in OSCI was revealed in both groups by the time of discharge from the hospital: from 4.0 [3.0, 4.0] points to 1.0 [1.0, 2.0] points in the MG ( p < 0.05) and from 3.0 [3.0, 4.0] points to 2.0 [2.0, 2.0] points in the CG ( p < 0.05).

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A larger percentage of cases with positive reverse transcriptase–PCR (RT-PCR) to SARS-CoV-2 was detected in the MG (43.3 versus 28.3% in the CG), but the difference did not reach statistical significance.

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