Barely Significant
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The Effect of Oral Semaglutide on Cardiovascular Risk Factors in Patients with Type 2 Diabetes: A Systematic Review.

J Clin Med · 2025 · PMC11990051 · PMID 40217690

Europe PMCDOI
2
hedged sentences
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

The sentences

an increasing trendp < 0.0001actually significant
HDL cholesterol shows the least consistent findings where three studies reported an increasing trend, yet this was not statistically significant; one study reported a mild increase in HDL (+0.90 ± 0.12; p < 0.0001); and one study reported a slight reduction in HDL (55.6 ± 2.5 to 51.6 ± 2.2; p < 0.05).

also in 63,971 other papers

showed a trendno p-value reported
et al.) [ 18 ] showed a trend in DBP reduction (−4.20 mmHg), while the other two studies (Husain M. et al. and Volpe S. et al.) [ 16 , 19 ] did not demonstrate statistically significant changes in DBP.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.