Additionally, the mRNA expression of Chac1 was increased in the ACTOO1 group relative to the HFD group, while the levels of Map3k13 and Hspa1b were decreased; however, these changes did not reach statistical significance (Fig. 9 C, D, E).
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Integrative transcriptomic and metabolomic analysis explores the mechanisms by which ACT001 treats MAFLD in mice.
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