Cardiometabolic index predicts cardiovascular events in aging population: a machine learning-based risk prediction framework from a large-scale longitudinal study.

Front Endocrinol (Lausanne) · 2025 · PMC11996631 · PMID 40235661

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did not reach statistical significanceno p-value reported

HbA1c demonstrated significant mediating effects for CVD (10.46%) and stroke (3.55%), but its mediation in the CMI-heart disease pathway did not reach statistical significance in the fully adjusted model.

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