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Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study.

Intensive Care Med Exp · 2025 · PMC11996739 · PMID 40229445

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Although the change did not reach statistical significance, the estimated shunt fraction slightly increased when PEEP was lowered.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.