The effect of doxepin 3 mg on sleep latency: a pooled analysis of two phase 3 trials.

Sleep Breath · 2025 · PMC11996978 · PMID 40229607

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did not reach statistical significanceno p-value reported

As with the objective LPS measured by PSG, the subjectively measured improvements in LSO did not exceed the 20-min threshold for clinical meaningfulness set out by AASM; they also did not reach statistical significance [ 8 ].

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