ACE2 and TMPRSS2 gene expression is reduced acutely in SARS-CoV-2 patients but returns to normal with recovery.

Patients infected with SARS-CoV-2 had lower ACE2 expression during the acute phase compared to the late convalescent phase, though this did not reach statistical significance (median relative expression 0.004 (7.46 × 10 − 7 -11.747) vs. 0.374 (2.6 × 10 − 7 -26.09), p = 0.103, respectively).

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