Pharmacological Treatment of Neuropsychiatric Symptoms in Huntington's Disease: A Systematic Review.

Mov Disord Clin Pract · 2025 · PMC11998698 · PMID 39891411

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

showed a trendP = 0.06so close (0.05 < p ≤ 0.1)

24 , 38 The same study showed a trend towards improvement of NPS on the UHDRS behavioral domain ( T 1,35 = 1.94, P = 0.06). 38 Open Label Studies Change in NPS composite score was a primary outcome in four open label studies. 41 , 42 , 43 , 45 All these studies reported a significant improvement of NPS (Table 3 ).

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a possible trendno p-value reported

P values 0.05 < P < 0.10 were considered a possible trend towards effective treatment.

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