There was a strong trend for DAMGO to suppress the frequency of GABA transmission equally well in slices from D2- Oprm1 tm1.1Cgrf mice and Adora2a-Cre +/− controls (Drug, F 1,11 = 4.26, p = 0.06; Drug x Genotype, F 1, 11 = 1.61, p = 0.23; Fig. 2C , E ).
← all excerpts
Mu opioid receptors expressed in striatal D2 medium spiny neurons have divergent contributions to cocaine and morphine reward.
1
—
—