Neural energy coding patterns of dopaminergic neural microcircuit and its impairment in major depressive disorder: A computational study.

PLoS Comput Biol · 2025 · PMC12002636 · PMID 40193386

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The simulation results of the actual energy ( Figs 4a , 4b and S1d ) showed a trend similar to that of the ionic energy [ 17 ]: As the dopamine concentration input rose, the actual energy consumption of the Pyra neuron also increased, while the actual energy consumption in NC group was significantly higher than that in MDD group (MDD=0.102 nJ, NC=0.178 nJ.

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