Histone methyltransferase SMYD2 regulates the activation of hepatic stellate cells by activating TLR4 signaling.

According to the experimental results, the expression levels of Smyd2 and H3K36me2 in the 9-week group significantly increased compared to the 6-week group, whereas the expression levels of Acta2, Col1a1, Tlr4, NF-κB p65, and NF-κB p-p65 exhibited an increased but did not reach statistical significance.

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