Surgery and neoadjuvant therapy in locally advanced pancreatic cancer: an umbrella review of survival, resection outcomes, and cost-effectiveness.

Gland Surg · 2025 · PMC12004333 · PMID 40256480

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did not reach statistical significanceno p-value reported

Similarly, the NEOPAN study indicated a trend toward improved PFS with FOLFIRINOX, although the OS benefit did not reach statistical significance ( 44 ).

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