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Nanoodor Particles Deliver Drugs to Central Nervous System via Olfactory Pathway.

Adv Sci (Weinh) · 2025 · PMC12005826 · PMID 39998409

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We observed the epithelial structure of the olfactory region (Figure 7b ) and revealed a clear trend in the distribution of the drug within the mucosa at 0.5, 1, and 60 min postadministration using confocal microscopy, showing that the nanoodors progressively diffused toward the brain over time (Figure 7c ).

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