Large clones of clonal hematopoiesis affect outcome in mantle cell lymphoma: results from the FIL MCL0208 clinical trial.

M-CH affects hematological recovery after ASCT Despite that no significant differences emerged between patients who are M-CH + and those who are M-CH − at baseline in terms of hematological toxicity after induction chemotherapy or overall hematological recovery after ASCT ( Table 2 ), interestingly, patients who are M-CH + exhibited a near-significant trend to a delayed thrombocytes recovery after ASCT compared with the remaining cohort (median days from ASCT to platelet count of ≥20 × 10 9 /L: 15 vs 13, respectively; P = .053).

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