“a near-significant trend”

A near-significant trend towards increasing Mediterranean diet adherence across time was observed in ACS patients (MEDAS mean score at inclusion: 8.8 ± 1.6; at 12-months: 9.8 ± 1.6; p = 0.05.

There was a near-significant trend for App group patients to perceive “slightly or much better health” over the last year, while most no-App patients considered their health unchanged ( P = .05) ( Figure 6B ).

Nonetheless, a near-significant trend was observed in the overall response rate (68.6% vs. 33%; p = 0.053) and a significant decrease in Ki67 levels (75% vs. 26.7%; p = 0.021) in the subgroup of patients with HR+/HER-2+ tumors.

A near-significant trend could also be observed for pain localized in the upper abdomen ( p = 0.055, Table 4 ).

Association between measures of sleep, cognition and quality-of-life After adjustment for age and history of COVID-19-related hospitalization, lower performance on NIH Toolbox attention test was associated with lower sleep efficiency (β = 0.55, p = 0.039) and a near-significant trend with longer sleep latency (β = −1.55, p = 0.058), while lower processing speed was associated with lower sleep efficiency (β = 1.27, p = 0.004), longer sleep latency (β = −0.31, p = 0.027), more WASO (β = −0.31, p = 0.025), and more awakenings (β = −0.56, p = 0.016).

For excess weight, the probability was also greater but a with a near-significant trend (0.19%; 95% CI = −0.01–0.39%, P = 0.059).

The difference in PFS benefits across treatment line subgroups was observed as a near-significant trend (P = 0.070) ( Figure 2B ). 3.3.

We did observe a near-significant trend toward a change in diversity associated with blood type (Bray-Curtis distance, PERMANOVA, P = 0.072, F = 1.500).

However, LV-BP was associated with a near-significant trend toward increased odds of adequate preparation among patients hospitalized with gastrointestinal bleeding (adjusted OR: 1.65 [95% CI: 0.94–2.91]; P = 0.08).

Recent ED visits in the last six months showed a near-significant trend (χ2 = 4.982, p = 0.083).

Probabilities of p ≤ 0.05 were significant and 0.05 < p ≤ 0.10 were a near-significant trend.

However, we did find a near-significant trend of decreasing APTT, which may hint that despite the neutral findings in the TEG-measurements, the intrinsic cascade may be affected, which is in alignment with earlier research [ 26 , 27 ].

However, post-hoc analyses demonstrated (1) a significant improvement in true local recurrence rates with pre-operative RT; (2) a potential loss of statistical power to detect abdominal recurrence free survival (ARFS) benefit due to poor RT protocol compliance; (3) a near-significant trend towards ARFS benefit for patients with well-differentiated liposarcomas and other low-grade histologies, a trend which achieved statistical significance on inclusion of an expansion cohort [ 11 – 13 ].

A near-significant trend for female sex was also noted.

Probabilities ( P ) of ≤ 0.05 were considered statistically significant, whereas values of 0.05 < P < 0.10 were declared a near-significant trend.

Significance was declared at p (probability) < 0.05, and 0.05 ≤ p < 0.10 was considered a near-significant trend. 3.

Although this suggests a near-significant trend, the result is not statistically significant.

Differences were considered significant at P < 0.05; P < 0.1 was taken to indicate a near-significant trend.

The only exception to this null finding in the current study is a near-significant trend that suggests the possibility that larger studies could find a weak relationship between adaptive characteristics and bouncing back from posttraumatic symptoms.

In response to compound 1 treatment, in addition to the above-mentioned CD8 + T cell expansion, we observed an increased frequency of NK cells in a near-significant trend (Figure 2 D, clus_3, blue vs. black) and a decreased frequency of pro-tumorigenic M2-like macrophages 41 (clus_8, blue vs. black), which supports tumor suppression due to compound 1 treatment.

The exposure of endothelial cells to monodansylcadaverine did not reduce the uptake rate of ApoExos or ApoBodies but did reduced transferrin, a protein known to enter cells through clathrin-dependent endocytosis, and ExoN to a near-significant trend (Fig. 3A ).

In all statistical analyses, differences were considered significant at p < 0.05; p < 0.1 was considered to indicate a near-significant trend. 3.

Differences were considered significant when P < 0.05, whereas P < 0.10 were considered a near-significant trend.

Differences were regarded as significant at p ≤ 0.05, while 0.05 < p ≤ 0.10 was considered a near-significant trend.

A T-probability of p ≤ 0.05 was considered statistically significant, while 0.05 < p ≤ 0.10 indicated a near-significant trend.