Circulating Tumor DNA and Response to Cisplatin-based Chemotherapy in Patients with Metastatic Urothelial Carcinoma Enrolled in CALGB 90601 (Alliance).

Eur Urol Open Sci · 2025 · PMC12008543 · PMID 40256659

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did not reach statistical significanceno p-value reported

Oncogenic ERCC2 alterations in cfDNA were observed in only nine cases (4.5%), compared to 11% in the TCGA [20] , and associations between ERCC2 and longer OS (HR 0.65; p = 0.3) and PFS (HR 0.58; p = 0.2) did not reach statistical significance.

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