We measured numerically lower CD8 + and CD4 + JCAR021 Cmax compared to JCAR014 at either dose level, although this did not reach statistical significance ( supplemental Table 11 ), and comparable transgene persistence ( supplemental Figure 4 ).
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Phase 1 study of CD19 CAR T-cell therapy harboring a fully human scFv in CAR-naïve adult patients with B-ALL.
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