A Multi-omics approach to identify and validate shared genetic architecture in rheumatoid arthritis, multiple sclerosis, and type 1 diabetes: integrating GWAS, GEO, MSigDB, and scRNA-seq data.

Funct Integr Genomics · 2025 · PMC12009781 · PMID 40254686

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0.0008

closest p · 0.0× alpha

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slightly significantP = 8.3 × 10 − 4actually significant

Additionally, there was a slightly significant negative correlation between RA and MS (correlation coefficient = -0.46, P = 8.3 × 10 − 4 ), and a slight but significant positive correlation between MS and T1D (correlation coefficient = 0.20, P = 0.041).

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