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Plasma extracellular vesicle neurofilament light chain as the biomarkers of the progression of Parkinson's disease.

Biomol Biomed · 2025 · PMC12010974 · PMID 39652080

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showed a trendno p-value reported
Specifically, blood EV NfL in PwP showed a trend toward correlation with the severity of akinetic rigidity (AR), while PwP in the lowest quartile of EV NfL levels had lower Unified PD Rating Scale (UPDRS) Part III scores after adjustments for age, sex, and disease duration [ 25 ].

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