In our case, human FMR1 ‐deficient oligodendrocyte cultures showed a trend for reduced mTOR expression and a similar decrease of Akt1 mRNA, alluding to a potential dysregulation of this pathway upon loss of FMRP.
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The Fragile X Messenger Ribonucleoprotein 1 Regulates the Morphology and Maturation of Human and Rat Oligodendrocytes.
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