In vivo experiments showed a trend towards improved graft survival in the Rapa + miR-638-MSC-EV Ctr group (medium survival 14 days) compared to the Rapa + MSC-EV Ctr group (medium survival 11 days), although the difference was not statistically significant ( Supplementary Figure 4D , Supplementary Table 3 ).
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Mixed lymphocyte reaction-conditioned MSC-derived extracellular vesicles enhance graft survival via miR-638-mediated immunoregulation.
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